Minggu, 10 April 2011

Calcium Dynamics in Inner Ear Health and Disease: An introduction to molecular mechanisms involved in genetic deafness

Calcium Dynamics in Inner Ear Health and Disease: An introduction to molecular mechanisms involved in genetic deafness


Calcium ion (Ca2+) acts as a fundamental signal transduction element in the inner ear, delivering information about sound, acceleration and gravity through a small number of mechano-transduction channels in the hair cell stereocilia as far as to the ribbon synapse, where it drives neurotransmission. The genetic approach is proving fundamental in unravelling the molecular

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